Progress in pathogenesis of patent ductus arteriosus in preterm infants
10.3760/cma.j.issn.2095-428X.2014.01.017
- VernacularTitle:早产儿动脉导管未闭发病机制研究进展
- Author:
Jinzhang ZHAO
1
;
Mingxia LI
Author Information
1. 新疆医科大学第一附属医院新生儿科
- Keywords:
Preterm infant;
Patent ductus arteriosus;
Pathogenesis
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(1):60-63
- CountryChina
- Language:Chinese
-
Abstract:
Patent ductus arteriosus is one of the common complications in the premature infants,which lead to or worsen respiratory distress,chronic pulmonary disease,intraventricular hemorrhage and necrotizing enterocolitis.It is associated with an increase in mortality and sequelae of preterm infants.The various factors contributing to an patency of the ductus arteriosus in the preterm infants are involved in:insufficient histological development of ductus arteriosus,failure of remodeling the ductus,abnormal sensitivity of the ductus to oxygen and vasoactive substances,and genes.It has been proposed a new idea that platelet induces or drives the closure of patent ductus arteriosus.
