Analysis of the difference of risk factors between each stage of necrotizing enterocolitis
10.3969/cma.j.issn.2095-428X.2013.19.013
- VernacularTitle:新生儿坏死性小肠结肠炎各期危险因素差异分析
- Author:
Xiao-Nan XU
1
;
Shao-Ru HE
;
Man-Li ZHENG
;
Lin LI
;
Yu-Mei LIU
;
Yun-Xia SUN
Author Information
1. 广东省医学科学院广东省人民医院新生儿科
- Keywords:
Necrotizing enterocolitis;
Risk factor;
Prognosis
- From:
Chinese Journal of Applied Clinical Pediatrics
2013;28(19):1483-1486
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the differences of the risk factors between Bell Stage Ⅰ and Stage Ⅱ/Ⅲ of neonatal necrotizing enterocolitis (NEC),in order to provide theoretical basis for better preventing and treating NEC of each stages.Methods Eighty seven NEC neonates'references from 2009 to 2011 were all analyzed retrospectively to find out relative risk factors.They were divided into 2 groups according to Bell stage:stage Ⅰ and stage Ⅱ/Ⅲ.Twenty four items were compared between the 2 groups,including perinatal factors,feeding methods,complications,RBC perfusion,etc,using SPSS 17.0 software to make single factor analysis,for the sake of finding out relative risk factors.Results The comparison of gestational age,birth weight,onset age,and onset weight between 2 groups has no statistical significance (P ＞ 0.05).The mortality of stage Ⅱ / Ⅲ was higher than stage Ⅰ (P ＜ 0.05).Seven of 24 items have statistical difference in the comparison (P ＜ 0.05),including:Gestational diabetes mellitus,amniotic fluid disorders,respiratory failure,hypothyroid,anemia,sepsis,RBC perfusion,indicating that these items may correlate to incidence and severity of NEC.Conclusions Gestational diabetes mellitus,amniotic fluid disorders,respiratory failure,hypothyroid,anemia,sepsis,RBC perfusion are risk factors that influence the severity of NEC.
