Latest study progress of umbilical cord-derived mesenchymal stem cells treating neonatal hypoxic-ischemic brain damage
10.3760/cma.j.issn.2095-428X.2013.14.021
- VernacularTitle:脐带间充质干细胞移植治疗新生儿缺氧缺血性脑损伤的最新研究进展
- Author:
De-Shuang ZHANG
1
;
Hua WANG
;
Xiao-Hong BAI
;
Juan CHEN
Author Information
1. 四川大学华西第二医院新生儿科
- Keywords:
Umbilical cord;
Mesenchymal stem cell;
Treatment;
Hypoxic-ischemic encephalopathy;
Infant,newborn
- From:
Chinese Journal of Applied Clinical Pediatrics
2013;28(14):1112-1114
- CountryChina
- Language:Chinese
-
Abstract:
Severe neonatal hypoxic-ischemic encephalopathy (HIE)can result in serious outcomes including death during the newborn period and permanent neuropsychological handicaps in the form of cerebral palsy,learning disability,epilepsy and so on.So far,there have been no effective treatments in clinical practice.Stem cell transplantation therapy brings new hope for HIE treatment.Among them,umbilical cord-derived mesenchymal stem cells have many advantages such as rich source,easy collection,shorter doubling time,lower immunogenicity and long-term survi-val after transplantation,it will have a broad application prospects as a cell source for the treatment of neonatal HIE.
