Study progress of sequelaes and risk factors of bacterial meningitis in children

VernacularTitle:儿童细菌性脑膜炎的后遗症及其危险因素研究进展
Author: Jin-Jing ZHANG ¹ ; Ya-Juan WANG
Author Information

1. 100045,首都医科大学附属北京儿童医院新生儿中心
Keywords: Bacterial meningitis; Sequelae; Risk factor; Child
From: Chinese Journal of Applied Clinical Pediatrics 2013;28(12):939-942
CountryChina
Language:Chinese
Abstract: Bacterial meningitis in children is still a life-threatening disease which causes a serious of sequelaes,the median risk of at least 1 major or minor sequelae after hospital discharge is 19.9％,including hearing impairment,cognitive impairment,motor disorders,seizures,visual impairment and so on.Of all these sequelaes,hearing impairment is the most common type.Multiple sequelae is recognized.Prognostic factors are found to be statistically significant:coma/impaired consciousness,complaints ＞ 48 hours before admission,seizures at admission,peripheral circulatory failure,respiratory distress,Streptococcus pneumonia as causative pathogen were recognized as the risk factors for sequeales.And cerebrospinal fluid parameters and white blood cell count were closely related to sequelaes.Hypokaliemia at admission also indicate poor prognosis,but need independent validation in clinical works.Male gender and corticoids were still in discussion.