Rathke cleft cysts in 22 children diagnosed by pituitary magnetic resonance
10.3760/cma.j.issn.2095-428X.2013.08.012
- VernacularTitle:垂体磁共振诊断儿童Rathke囊肿22例
- Author:
Lei LJ
1
;
Meng-Meng HAO
;
Zhi-Hong CHEN
;
Tang LI
Author Information
1. 266003,青岛大学医学院附属医院儿内科
- Keywords:
Rathke cleft cysts;
Clinical manifestation;
Pituitary magnetic resonanc;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2013;28(8):600-602
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical features of Rathke cleft cysts(RCCs) in children diagnosed by pituitary magnetic resonance(MR) and their features on MR.Methods Twenty-two children with RCCs aged 2-18 years old who visited the Affiliated Hospital of Qingdao University Medical College between Jan.2002 and Feb.2012 were enrolled.RCCs was conformed by pituitary MR.The clinical symptoms and imaging features were reviewed retrospectively.Results The clinical presentation of symptomatic children were as follows:endocrinopathy in 13 cases (59.1％),headache in 5 cases(22.7％) and visual disturbance in 1 case(4.5％) and variety of symptoms in 3 cases (13.6％),which including 1 case of short stature and dysgenitalism,1 case of type 1 diabetes with electrolyte disorder and the other of headache associated with visual impairment.Endocrinopathy included short stature 5 cases(22.7％),precocious puberty 4 cases(18.2％)and diabetes insipidus 4 cases(18.2％).Generally,RCCs appeared various on Tl-weighted MR,whereas on T2-weighted sequences the signal intensity was mostly high.High signals in the T1-weighted image on brain MR were related to pituitary hormone deficiency.Hypointensity of the cysts in T1-weighted was appeared when enhanced images.Conclusions The most common clinical manifestation of children with RCCs is endocrinopathy.Pituitary MR shows a certain characteristics and it is favorable in agreement with pathological diagnosis.MR may be of predictive value for the preoperative diagnosis.
