Advances of stanniocalcin 2 in tumors
10.3760/cma.j.issn.1673-422X.2018.10.008
- VernacularTitle:斯钙素2在肿瘤中的研究进展
- Author:
Jishang YU
1
;
Fan WU
Author Information
1. 510220,暨南大学医学院附属广州红十字会医院普通外科
- Keywords:
Neosplasms;
Cell proliferation;
Apoptosis;
Neoplasm metastasis;
Stanniocalcin 2
- From:
Journal of International Oncology
2018;45(10):615-618
- CountryChina
- Language:Chinese
-
Abstract:
Stanniocalcin 2,a secreted glycoprotein hormone,has been found to be highly expressed in a variety of human malignancies.Through several signal transdution pathways,stanniocalcin 2 plays important roles in the regulation of many biological events of tumor such as proliferation,apoptosis,invasion and metastasis,hypoxia tolerating and drug resistance,indicating stanniocalcin 2 may be a pivotal node in the molecular regulation network of tumor.Stanniocalcin 2 is expected to become a novel biomarker and therapeutic target for diagnosis and treatment of tumor if the funtional mechanisms of stanniocalcin 2 could be further elaborated.
