Streptococcus pneumoniae Isolates with Decreased Susceptibility to Optochin.
- Author:
Seungok LEE
1
;
Jung Joon PARK
;
Eun Jee OH
;
Yeon Joon PARK
;
Byung Kee KIM
Author Information
1. Department of Clinical Pathology, Kangnam St. Marys Hospital, The Catholic University of Korea, Seoul, Korea. yjpk@cmc.cuk.ac.kr
- Publication Type:Case Report
- Keywords:
Optochin;
Decreased susceptibility;
Streptococcus pneumoniae
- MeSH:
Adult;
Agglutination Tests;
Bile;
Conjunctivitis;
DNA;
Humans;
Meningitis;
Otitis Media;
Pneumonia;
Solubility;
Streptococcus pneumoniae*;
Streptococcus*
- From:Korean Journal of Clinical Microbiology
2002;5(1):59-61
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Streptococcus pneumoniae is the most common cause of community-acquired pneumonia in adults and an important agent in other infections, including meningitis, otitis media, and conjunctivitis, etc. The optochin susceptibility test is the most widely used method to discriminate S. pneumoniae from other streptococci. However, 0.8-1.5% of S. pneumoniae contain optochin resistant population. Recently, we experienced three cases of variants of S. pneumoniae with decreased susceptibility to optochin. Equivocal optochin disk test should be confirmed by bile solubility, agglutination test, or DNA probe test.