Vasculogenic mimicry dominated by tumors and migration and invasion of carcinomas
10.3760/cma.j.issn.1673-4203.2019.01.016
- VernacularTitle:肿瘤细胞主导的血管生成拟态与肿瘤侵袭转移
- Author:
Musheng RAO
1
;
Shenghua CAO
;
Xingdong XU
;
Gang WANG
;
Xuecheng WANG
Author Information
1. 三峡大学人民医院宜昌市第一人民医院普外科 443000
- Keywords:
Neoplasm metastasis;
Neoplasm invasiveness;
Vasculogenic mimicry
- From:
International Journal of Surgery
2019;46(1):60-63,封4
- CountryChina
- Language:Chinese
-
Abstract:
The growth of solid tumors is dependent on new blood vessels generated from existed ones,that is tumor angiogenesis.Much material consumption is required in the invasion and metastasis of malignant tumors,to meet the own needs of oxygen and nutrients and remove the metabolic wastes from them,tumor cells will generate new vasculature through different ways.Vasculogenic mimicry is a kind of angiogenesis dominated by tumor cells,it is one style of vascular pattern that is different from traditional endothelial cells pattern.Vasculogenic mimicry plays an important role in the invasion and metastasis of tumors.This article will review the relationship between vasculogenic mimicry and tumor invasion and metastasis,tumor angiogenesis,and related signaling pathways.
