Wnt/β-catenin signaling pathway and gastric cancer
10.3760/cma.j.issn.1673-4203.2018.12.013
- VernacularTitle:Wnt/β-catenin信号通路在胃癌中的研究进展
- Author:
Ling WANG
1
;
Luosha WANG
;
Jiwu GUO
;
Yumin LI
Author Information
1. 兰州大学第二医院消化系肿瘤实验室
- Keywords:
Stomach neoplasms;
Review;
Therapeutic uses;
Wnt/β-catenin signaling pathway
- From:
International Journal of Surgery
2018;45(12):841-845
- CountryChina
- Language:Chinese
-
Abstract:
Wnt/β-catenin signaling pathway is an evolutionarily conserved signaling pathway that plays an important role in embryonic and organ development,which is not only invovled in regulating several cellular proliferation,differentiation,polarity,migration and apoptosis,but aslo playing an critical role in initiation,invasion,metastasis,progression and drug resistance of gastric cancer.This article will review the newest studies about gastric cancer of Wnt/β-catenin and provide fundamenal theories to design new drugs for the treatment of gastric cancer.
