Epilepsy, Reactive Oxygen Species and Mitochondria.
- Author:
Won Seop KIM
1
Author Information
1. Department of Pediatrics, College of Medicine, Chungbuk National Universty, Cheongju, Korea.
- Publication Type:Review
- Keywords:
Epilepsy;
Reactive oxygen species;
Mitochondria
- MeSH:
Brain;
Epilepsy*;
Mitochondria*;
Mitochondrial Diseases;
Nervous System Diseases;
Oxidative Phosphorylation;
Oxidative Stress;
Reactive Oxygen Species*;
Seizures
- From:
Journal of the Korean Child Neurology Society
2005;13(1):1-7
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Epilepsy is a neurological disorder from many molecular and biochemical responses. In the underlying mechanism, reactive oxygen species play an important role in seizure initiation and seizure-induced brain damage. In mitochondrial diseases, epileptic seizures are also noted from defects of oxidative phosphorylation. So oxidative stress from reactive oxygen species is important in mitochondrial dysfunction and epileptic seizure.
