It has been suggested in a number of studies that penetrating abdominal stab wounds may be managed conservatively although only a few local studies support this claim. This study reviews experience based on 483 patients, who underwent celiotomy for a single penetrating abdominal stab wound inflicted by a single bladed knife from Jan. 1989 to June 1991. The cases were divided into two (2) groups, those who underwent celiotomy with indications and those who underwent celiotomy without indications. Tabulation of operative findings according to the location of the stab wound in the nine (9) regions of the anterior abdomen showed that 89% of all patients with indications for surgery had significant injury. In the group who underwent celiotomy without indications, 78% had positive findings. The data for groups A and B stratified into the nine regions did not show any significant difference in the frequency of abdominal injury except in the right lumbar, left lumbar, left iliac and umbilical region. In these last four regions, the frequency of abdominal injury in the group with indications is statistically higher than in the group without indications. Therefore, a trial of observation in these regions is therefore acceptable in the absence of indications for celiotomy.