A Preliminary Clinical Study Of Lesion-Free And Lesion-Active Patients With Oral Lichen Planus And/Or Oral Lichenoid Reactions
- Author:
Foo SY
1
;
Lee WY
;
Goh YC
;
Siar CH
Author Information
1. Oral Health Division, Ministry of Health Malaysia, Kuala Lumpur, Malaysia
- Publication Type:Original article
- Keywords:
Clinical features;
demographic profile;
lesion-free vs lesion-active;
oral lichen planus and oral lichenoid reaction
- From:
Annals of Dentistry
2015;22(1):21-29
- CountryMalaysia
- Language:English
-
Abstract:
Background: Oral lichen planus (OLP) which belongs to the spectrum of LP, is a commonly encounteredoral mucosal problem among patients seeking treatment in the Oral Medicine clinic. Its counterpart, orallichenoid reaction (OLR), which resembled OLP clinically and microscopically, is often encountered inthese patients as well. Although the various clinical forms of OLP/OLR are well-recognized, the diseasepattern in regards to lesion-active and lesion-free periods in these patients remains poorly characterized.Thus the aim of this study was to determine the clinical and demographic profile of those patients withactive OLP/OLR lesions and compare them with those patients who are clinically lesion-free.Materials and methods: The study subjects comprised 20 patients who attended the Oral MedicineClinic at the Faculty of Dentistry, University of Malaya for follow-up appointments/management. Theywere interviewed according to a pre-designed questionnaire, and clinical examination was carried out. Allthese were conducted under the supervision of Oral Medicine specialists. OLP was diagnosed accordingto the internationally accepted criteria.Results: The cohort consisted of predominantly female (n=14; 70%) and Chinese (n=9; 45%) patients,with an overall age range of 26-79 years (median, 56 years). Fifteen (75%) patients presented withactive OLP/OLR lesions and the remaining 5 (25%) were lesion-free. The lesion-active group comprised3 (15%) males and 12 (60%) females whereas the lesion-free had 3 (15%) males and 2 (10%) females.Reticular LP was the most common type (n=21/35; 60%) and the gingiva was the most prevalent site(n=21/46; 45.65%). Social habits, medical histories and medications were not significantly differentbetween lesion-active and lesion-free OLP patients.Conclusions: Findings suggest that demographic parameters, lifestyle and systemic diseases do notappear to influence the disease pattern and lesion severity in OLP.
