Research Progress of Toll-like Receptors and Cerebral Ischemia

VernacularTitle:Toll样受体与脑缺血
Author: Sujun ZHANG ¹ ; Yuzhe GAO ; Zhiyao WEI ; Changhe LAI ; Junwen CHENG ; Xiaohui DING
Author Information

1. 沈阳医学院基础医学院麻醉学专业2012级3班
Keywords: Toll-like receptors; cerebral ischemia; signal transduction; clinical treatment
From: Journal of Shenyang Medical College 2016;18(4):305-308
CountryChina
Language:Chinese
Abstract: Cerebrovascular disease is one of the main diseases that threaten human health and life,and the age of onset become younger and younger. Research shows that Toll-like receptors (TLRs) express in brain, have effects on neurons, play an important role in the occurrence and development of cerebral ischemia and secondary cerebral injury.It is clear that TLR2, TLR3, TLR4, TLR7 and TLR9 have influence on occurrence and development of cerebral ischemia. This is crucial for understanding the relationship between immune inflammation and nerve regeneration, and improving clinical treatment.