Clinical Efficacy of Inhaled Nitric Oxide in the Treatment of Persistent Pulmonary Hypertension of the Newborn and Nursing
10.16753/j.cnki.1008-2344.2016.04.017
- VernacularTitle:一氧化氮吸入治疗新生儿持续肺动脉高压的效果观察及护理
- Author:
Yu LIN
1
;
Xiaoyan LIN
Author Information
1. 广东省茂名市妇幼保健院新生儿科
- Keywords:
nitric oxide;
newborn;
persistent pulmonary hypertension;
clinical efficacy;
nursing
- From:
Journal of Shenyang Medical College
2016;18(4):276-278
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analysis clinical efficacy of inhaled nitric oxide in the treatment of persistent pulmonary hypertension of the newborn and nursing. Methods: A total of 84 cases of persistent pulmonary hypertension of the newborn received high-frequency oscillation mode of mechanical ventilation at higher ventilation parameters,and inhaled nitric oxide therapy. Before inhalation of nitric oxide and 30 min, 24 h after inhalation of nitric oxide, transcutaneous oxygen saturation (SpO2), blood gas analysis,blood pressure,heart rate,mean arterial blood pressure and oxygenation index (OI) were recorded. Results:There was significant difference in SpO2,PaO2,PaCO2,FiO2,OI at 30 min and 24 h after inhalation of nitric oxide (P<0.05) . There was no significant difference in HR,SPAP,SBP,MAP,pH (P>0.05) .Conclusion:Inhaled nitric oxide combined with a high-frequency oscillation mode of mechanical ventilation in newborns with persistent pulmonary hypertension significantly improve OI,blood gas analysis,oxygen saturation and other indicators,and effective interventions can avoid nitric oxide-related adverse reactions.
