Research Progress of Human Epidermal Growth Factor Receptor-2 and Vascular Endothelial Growth Fac-tor in Colon Cancer
10.16753/j.cnki.1008-2344.2016.03.020
- VernacularTitle:人表皮生长因子受体2与血管内皮生长因子在结肠癌中的研究进展
- Author:
Yu GE
1
;
Jiasheng? ZHU
Author Information
1. 皖南医学院弋矶山医院胃肠外科
- Keywords:
human epidermal growth factor receptor-2;
vascular endothelial growth factor;
colon cancer
- From:
Journal of Shenyang Medical College
2016;18(3):187-190
- CountryChina
- Language:Chinese
-
Abstract:
Human epidermal growth factor receptor?2 ( Her?2) plays an important role in promoting the growth of tumor cells and inhibiting cell apoptosis. Vascular endothelial growth factor ( VEGF) can not only promote the formation of vessels and lymphatic ves?sels, but also promote lymphatic metastasis. They cooperatively promote invasiveness and metastasis. Now Her?2?interference RNA, molecular target therapy and VEGF anti?lymphatic therapy have become a new treatment for colon cancer.