Prevention experience of biliary tract complications after liver transplantation from organ donation after citizen's death
10.3969/j.issn.1674-7445.2017.04.009
- VernacularTitle:公民逝世后器官捐献供肝移植胆道并发症的预防经验
- Author:
Yuqiang WU
1
;
Zemin HU
;
Kun HE
;
Dongdong HUANG
;
Qiang SUN
;
Jiahou RUAN
;
Qijie LUO
;
Ruiqin HUANG
Author Information
1. 中山大学附属中山医院肝胆胰外科
- Keywords:
Organ donation;
Liver transplantation;
Biliary tract stenosis;
Extracorporeal membrane oxygenation;
Ischemia time;
Donor liver procurement;
Immunosuppression;
Biliary tract stent
- From:
Organ Transplantation
2017;8(4):299-303
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the experience of prevention of biliary tract complications after liver transplantation from organ donation after citizen's death. Methods Clinical data of 88 cases undergoing liver transplantation from organ donation after citizen's death in the Affiliated Zhongshan Hospital of Sun Yat-sen University from October 2008 to December 2016 were retrospectively analyzed. Results Eighty-eight cases were eligible for the standards for organ donation after brain death plus cardiac death according to the Ⅲ national system for organ donation in China. According to the standard procedures, donor livers were successfully harvested and transplanted in 88 recipients. The biliary tract was reconstructed using the bile duct end-to-end anastomosis. The length of bile duct in the donors was shortened as possible. Slight tension should be maintained during anastomosis. Neither primary liver graft nonfunction nor rejection reaction occurred. One recipient suffered from bile leakage and recovered after drainage for 3 weeks. Two patients presented with biliary tract stenosis and mitigated after the placement of biliary tract stent. Conclusions The harvesting of donor liver should be in accordance with the standard procedures. The advantages of extracorporeal membrane oxygenation (ECMO) should be fully utilized to shorten warm and cold ischemia time as possible. Much attention should be diverted to the reconstruction of biliary tract, which contributes to decreasing the risk of biliary tract complications. Favorable clinical efficacy can be achieved in liver transplantation from organ donation after citizen's death.
