Clinical efficacy of en-bloc kidney transplantation from infantile donor organs to adult recipients:report of two cases
10.3969/j.issn.1674-7445.2017.04.008
- VernacularTitle:婴幼儿公民逝世后器官捐献成人双肾移植的临床效果(附2例报告)
- Author:
Handong DING
1
;
Guiyi LIAO
;
Jinbiao ZHONG
;
Fei ZHAO
Author Information
1. 安徽医科大学第一附属医院泌尿外科
- Keywords:
Kidney transplantation;
Infant;
Organ donation after citizen's death;
Survival rate;
En-bloc kidney transplantation;
Compensatory hyperplasia;
Compensation rate;
Vascular anastomosis
- From:
Organ Transplantation
2017;8(4):295-298
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of en-bloc kidney transplantation from infantile organ donation after citizen's death to adult recipients. Methods Clinical data, surgical approach, use of immunosuppressive agents and follow-up of two adults undergoing kidney transplantation from infantile donor organs were retrospectively analyzed. Relevant literature review was performed. Results One male recipient was diagnosed with primary diseases of chronic renal lesions and renal failure. After kidney transplantation, the recipient obtained favorable recovery of kidney function. The grafted kidney was gradually increased in size. During the final follow-up (10 months after surgery), the serum creatinine level was measured as 84 μmol/L. The other female recipient was diagnosed with renal failure accompanied with uremia. The recipient died from heart failure complicated with severe pulmonary infection at postoperative 23 d. No vascular complications occurred in either recipient. Conclusions Kidney transplantation from infantile donor organs to adult recipients yields favorable clinical efficacy and the grafted kidney is significantly increased in size during the early stage. Precise intraoperative manipulation contributes to preventing the incidence of arterial embolism of the donor kidney and other postoperative complications.
