Clinical experience analysis of liver transplantation from donation after citizen’s death in 78 cases
10.3969/j.issn.1674-7445.2016.04.008
- VernacularTitle:公民逝世后器官捐献肝移植78例临床经验分析
- Author:
Chuan LAN
1
;
Ming ZHANG
;
Lyunan YAN
;
Bo LI
;
Yong ZENG
;
Tianfu WEN
;
Mingqing XU
;
Wentao WANG
;
Jiayin YANG
Author Information
1. 四川大学华西医院肝脏外科 肝脏移植中心
- Keywords:
Organ donation after citizen’s death;
Liver transplantation;
Early allograft dysfunction;
Cold ischemia time;
Selection of donor liver;
Clinical study,practice;
Total bilirubin
- From:
Organ Transplantation
2016;7(4):287-291
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical experience and effect analysis of liver transplantation from donation after citizen’s death. Methods Clinical data of 76 donors and 78 recipients of liver transplantation from donation after citizen’s death completed in Liver Transplantation Center of West China Hospital,Sichuan University from March 2012 to November 2015 were analyzed retrospectively.The functional recovery of early allografts in liver transplant recipients was observed and the risk factors causing early allograft dysfunction (EAD)were analyzed.In addition,long﹣term survival of allografts and recipient as well as complications was observed. Results The incidence of postoperative EAD was 36%(28 /78)in 78 recipients.High total bilirubin (TB)and long cold ischemia time constituted the risk factors of EAD. Survival rate of the recipients was 92% (72 /78)during perioperation,and 6 cases died,of which 4 cases died of primary graft dysfunction,1 case of upper gastrointestinal hemorrhage and 1 case of pulmonary infection.Postoperative abdominal infection occurred in 5 cases,with biliary stricture in 3 cases and vascular thrombosis in 2 cases.One case died,and the rest were improved after corresponding treatment.The 1﹣year survival rate of the recipients was 84.2% and 2﹣year survival rate was 80% after operation. Conclusions Liver transplantation from donation after citizen’s death realizes favorable short and long﹣term effects,which can be regarded as a good source of donor livers.Important measures such as controlling the preoperative quality of donor liver and shortening the cold ischemia time can improve the clinical effect.
