Application of fast perfusion through abdominal aorta and portal vein in combined liver and kidney procurement from organ donation
10.3969/j.issn.1674-7445.2015.01.011
- VernacularTitle:腹主动脉联合门静脉快速灌注法在器官捐献供体肝肾联合获取中的应用
- Author:
Feiwen DENG
1
;
Huanwei CHEN
;
Zuojun ZHEN
;
Fengjie WANG
;
Jieyuan LI
;
Jianyuan HU
;
Yong JI
Author Information
1. 528000,广东佛山市第一人民医院肝脏胰腺外科
- Keywords:
Organ donation;
Abdominal aortic cannulation perfusion;
Portal vein perfusion;
Combined liver and kidney procurement
- From:
Organ Transplantation
2015;(1):51-54,58
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the feasibility and safety of fast perfusion through abdominal aorta and portal vein in combined liver and kidney procurement from organ donation. Methods Clinical data of 43 donors of donation after cardiac death (DCD)undergoing combined liver and kidney procurement in the First People’s Hospital of Foshan from September 201 1 to June 2014 were analyzed retrospectively. Among the 43 donors,15 cases were China DCD donor category Ⅰ (donor after brain death) (C-Ⅰ),1 case was category Ⅱ (donor after cardiac death) (C-Ⅱ)and 27 cases were categoryⅢ(C-Ⅲ). Combined abdominal aorta and portal vein perfusion with fast cannulation were performed. Results The time from abdomen incision to abdominal aorta cannulation was 1.5-2.0 min. Forty-three livers and eighty-six kidneys were procured from 43 donors. The warm ischemia time (WIT)was 0 for C-Ⅰ donors,and was 3-21 min for the other donors (mean:10 min). Two liver grafts were discarded for major injury of the porta hepatis and severe fatty liver respectively. Eighteen kidney grafts were discarded for kidney stones, kidney atrophy, high level of preoperative serum creatinine,severe renal atherosclerosis,renal microvessel thrombosis,multiple renal cyst, kidney traumatic rupture,etc. The total discard rate of donor organs was 16%. Conclusions Fast perfusion through abdominal aorta and portal vein is a simple and safe method in combined procurement liver and kidney from organ donation.
