Effect evaluation of mechanical perfusion in the application of renal transplantation：a report of 36 cases
10.3969/j.issn.1674-7445.2014.03.012
- VernacularTitle:机械灌注应用在肾移植中的效果评价（附36例报道）
- Author:
Qiang YAN
1
;
Xiaolian WEI
;
Fei LI
;
Ming YANG
;
Huaizhou CHEN
;
Shenping XIE
;
Junjun GUO
;
Ping LIU
;
Feng SHI
;
Weiguo SUI
Author Information
1. 解放军第181 医院肾脏科 全军器官移植与透析治疗中心 广西省代谢性疾病研究重点实验室
- Keywords:
Mechanical perfusion;
Renal transplantation;
Delayed graft function;
Resistance coefficient;
Flow velocity
- From:
Organ Transplantation
2014;(3):182-185
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical effect of mechanical perfusion for preserving kidney.Methods From May to October 2013, 36 donors’ kidneys were preserved by mechanical perfusion in the Department of Kidney in the 181st Hospital of Chinese People's Liberation Army.The donors’ kidneys were preserved , transported and perfused by the LKT-100 type Lifeport organ transporter and special software.General condition of patients and the relationship between resistance coefficient , flow velocity and occurrence of delayed graft function ( DGF) were analyzed.Results None of 36 recipients had graft loss.Thirty cases ’ (83%) renal function recovered well without DGF.Six cases developed DGF and returned to normal gradually after 3-18 days postoperative treatment.After mechanical renal perfusion for 1 h, 28 recipients with kidneys ’ resistance coefficient ≤0.3 mmHg/( ml · min ) hadn't developed DGF after transplantation.Among 8 recipients with kidneys ’ resistance coefficient >0.3 mmHg/( ml · min ) , 6 recipients developed DGF.Eight recipients with kidneys ’ flow velocity >100 ml/min hadn't developed DGF.Among 21 recipients with kidneys ’ flow velocity 60-100 ml/min, 1 case developed DGF.In 7 recipients with kidneys ’ flow velocity <60 ml/min, 5 cases developed DGF.Conclusions Mechanical perfusion for preserving kidney can improve graft quality and reduce the incidence of DGF in recipients.
