Effects of different oxygen therapies on conservative treatment of spontaneous pneumothorax: A systematic review and meta-analysis
10.7507/1007-4848.201804050
- VernacularTitle:不同吸氧方式对保守治疗自发性气胸疗效的 系统评价与Meta 分析
- Author:
CAO Xiong
1
,
2
;
LI Xiuxia
3
,
4
,
5
;
LIN Ruijiang
6
;
YANG Kehu
5
,
7
;
HAN Biao
6
Author Information
1. 1. First Clinical Medical College, Lanzhou University, Lanzhou, 730000, P.R.China
2. 2. First Hospital, Lanzhou University, Lanzhou, 730000, P.R.China
3. 3. School of Public Health, Lanzhou University, Lanzhou, 730000, P.R.China
4. 4. Evidence-based Medicine Center, Lanzhou University/School of Basic Medical Sciences, Lanzhou University, Lanzhou, 730000, P.R.China
5. 5. The Key Laboratory of Evidence-based Medicine and Clinical Transformation, Gansu Province, Lanzhou, 730000, P.R.China
6. First Hospital, Lanzhou University, Lanzhou, 730000, P.R.China
7. 4. Evidence-based Medicine Center, Lanzhou University/School of Basic Medical Sciences, Lanzhou University, Lanzhou, 730000, P.R.China
- Publication Type:Journal Article
- Keywords:
Spontaneous pneumothorax;
oxygen therapy;
meta-analysis;
randomized controlled trial
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2019;26(3):245-250
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of two different oxygen therapies (oxygen time<4 h/d, oxygen flow>6 L/minversus oxygen time>4 h/d, oxygen flow<6 L/min) on conservative treatment of spontaneous pneumothorax by meta-analysis. Methods The following electronic databases as PubMed, The Cochrane Library, Web of Science, Chinese Biomedical Literature Database, WanFang Database and China National Knowledge Database were retrieved on computer for randomized controlled trials (RCTs) of comparing two different oxygen therapies (oxygen time<4 h/d, oxygen flow>6 L/minversus oxygen time>4 h/d, oxygen flow<6 L/min) on conservative treatment of spontaneous pneumothorax. The retrieval time was from inception of each database to December 2017. Two reviewers independently screened literature according to the inclusion and exclusion criteria, extracted data, and assessed the methodological quality of the included studies. Then data were analyzed by RevMan 5.3 software. Results A total of 4 RCTs involving 226 patients were included. The meta-analysis showed that compared with lower oxygen flow (oxygen time>4 h/d, oxygen flow<6 L/min), the higher oxygen flow (oxygen time<4 h/d, oxygen flow>6 L/min) could obviously decrease the degree of pulmonary compression after oxygen therapy for 5 days (MD=–2.81, 95%CI –4.18 to –1.44, P<0.05), shorten duration of hospital stay (MD=–3.26, 95%CI –6.05 to –0.47, P<0.05) and duration of recruitment maneuvers (MD=–2.78, 95%CI –5.27 to –0.28, P<0.05), but there was no significant difference in oxygen partial pressure after oxygen therapy for 5 days (MD=10.68, 95%CI –7.03 to 28.39, P=0.24). Conclusion The higher oxygen flow (oxygen time<4 h/d, oxygen flow>6 L/min) can obviously decrease the degree of pulmonary compression after oxygen therapy for 5 days, shorten duration of hospital stay and duration of recruitment maneuvers, but the results are influenced by the number and quality of RCT.
