Progression of MAPK signal pathway in eye wound
10.3980/j.issn.1672-5123.2017.3.17
- VernacularTitle:MAPK信号通路与眼部损伤研究进展
- Author:
Bo-Yuan Yao
1
,
2
Author Information
1. 1Department of Ophthalmology, the Second Hospital of Jilin University, Changchun 130041, Jilin Province, China
2. 2Norman Bethune Health Science Center of Jilin University, Changchun 130021, Jilin Province, China
- Publication Type:Journal Article
- Keywords:
MAPK;
cornea;
retina;
wound
- From:
International Eye Science
2017;17(3):458-462
- CountryChina
- Language:Chinese
-
Abstract:
Mitogen-activated protein kinase(MAPK)signal pathway family are important signal transduction pathways, which widely exit in cells. They are able to make particular physiological responses induced by multiple extracellular signals or stimulus, such as changes of osmotic pressures, ischemic/reperfusion, inflammation and so on, that means they can mediate cell proliferation, differentiation and apoptosis. The physiological responses mediated by MAPK signal pathway make great scene to the progression and healing of eye wounds, therefore researchers may highlight the pathway in research.
