Alteration in ocular blood flow and its effect on the progression of glaucoma
10.3980/j.issn.1672-5123.2017.3.2
- VernacularTitle:眼血流的变化对青光眼病情进展的影响
- Author:
Sher Zaman Safi
1
Author Information
1. 1Interdisciplinary Research Centre in Biomedical Materials, COMSATS Institute of Information Technology, Lahore Campus, Lahore 54000, Pakistan2Women University, Multan 60000, Pakistan3Department of Medical Lab Sciences(DMLS), Faculty of Health and Allied Sciences, Imperial College of Business Studies, Lahore 54000, Pakistan4Medical College, Foundation University, Islamabad 44000, Pakistan5Biochemistry Section, Department of Chemistry, University of Peshawar, Peshawar 25000, Pakistan
- Publication Type:Journal Article
- Keywords:
ocular blood flow;
glaucoma;
disease progression
- From:
International Eye Science
2017;17(3):394-398
- CountryChina
- Language:Chinese
-
Abstract:
Glaucoma is a multifactorial neurodegenerative disease that can result in permanent vision loss by damaging optic nerves due to higher pressure in the eye. Although most of the fundamental pathophysiological mechanisms involved in glaucoma are undetermined but alteration in ocular blood flow(OBF)in tissues such as optic nerve, retina, choroid and iris is an important risk factor for glaucoma. Various factors such as limited knowledge of the factors causing optic nerve damage, confusion in the measurement assays and lack of therapies, make hindrances in the understanding of glaucoma. Researchers are continuously accumulating evidence to suggest that alterations in OBF play important role in the pathogenesis of glaucoma but most of the times they have diverse and contradictory conclusions regarding changes in the OBF and risk of glaucoma. In this article we have reviewed different aspects of glaucoma and the effect of OBF in the disease progression
