Effect of Partial Ligation of the Abdominal Aorta on the Glomerular Filtration Rate.
- Author:
Young YOON
1
Author Information
1. Department of Urology, National Medical Center, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
partial ligation of aorta;
GFR
- MeSH:
Anesthesia;
Aorta, Abdominal*;
Glomerular Filtration Rate*;
Humans;
Inulin;
Kidney;
Ligation*;
Male;
Pentobarbital;
Rabbits;
Renal Artery
- From:Korean Journal of Urology
1979;20(6):562-569
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Effect of partial ligation of the abdominal aorta on the glomerular filtration rate (inulin clearance) was observed in 17 male rabbits. Abdominal aorta was ligated to one-half of its original lumen at the level just above branching of the right renal artery under nembutal anesthesia. Seventeen rabbits were observed 30 minutes before the partial ligation, 30 minutes and 90 minutes after the partial ligation. The following results were obtained. 1. Inulin clearance observed 30 minutes before ligation was 1.02+/-0.90 ml/min (Mean+/-S. D.) or 0.52+/-0.46 ml/min/kg in average. 2. Inulin clearance observed 30 minutes after ligation was decreased markedly to 0.46+/-0.58ml/min or 0.23+/-0.29 ml/min/kg in average. 3. Inulin clearance observed 90 minutes after ligation was decreased-slightly to 0.77+/-0.79ml/min or 0.40+/-0.38ml/min/kg in average, suggesting that its findings were occurred by autoregulatory process of the kidney.