Necrotic lymphoma in a patient with post-transplantation lymphoproliferative disorder: ultrasonography and CT findings with pathologic correlation.
- Author:
Minsu LEE
1
;
Sang Kyum KIM
;
Yong Eun CHUNG
;
Jin Young CHOI
;
Mi Suk PARK
;
Joon Seok LIM
;
Myeong Jin KIM
;
Honsoul KIM
Author Information
- Publication Type:Case Report
- Keywords: Lymphoma; Ultrasonography; Immunocompromised host
- MeSH: Adult; B-Lymphocytes; Diagnosis; Follow-Up Studies; Humans; Immunocompromised Host; Kidney; Kidney Transplantation; Liver; Lymphoma*; Lymphoma, Non-Hodgkin; Lymphoproliferative Disorders*; Necrosis; Nephrotic Syndrome; Ultrasonography*
- From: Ultrasonography 2015;34(2):148-152
- CountryRepublic of Korea
- Language:English
- Abstract: Seventeen months after kidney transplantation for the treatment of nephrotic syndrome, a retroperitoneal mass was incidentally detected in a 30-year-old man during routine follow-up. Ultrasonography revealed a mass measuring 5.5 cmx4.3 cm located between the liver and the atrophic right kidney, which showed markedly heterogeneous internal echogenicity. Contrast-enhanced computed tomography displayed a mild degree of enhancement only at the periphery of the mass, while the center lacked perceivable intensification. The patient underwent surgical resection. The final pathological diagnosis was non-Hodgkin lymphoma (diffuse large B-cell lymphoma), and extensive necrosis was observed on microscopic examination. We found that the prominent heterogeneous echogenicity of the mass (an unusual finding of lymphoma) demonstrated on ultrasonography is a result of extensive necrosis, which may sometimes occur in patients with post-transplantation lymphoproliferative disorder.
