Simultaneous Lung and Liver Aspergillus in a Kidney Transplant Recipient.
10.4285/jkstn.2012.26.3.202
- Author:
Jihye PARK
1
;
Eunah HWANG
;
Sungbae PARK
;
Hyunchul KIM
;
Hyoungtae KIM
Author Information
1. Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea. eahwang@gmail.com
- Publication Type:Case Report
- Keywords:
Kidney transplantation;
Fungal;
Aspergillus
- MeSH:
Aspergillosis;
Aspergillus;
Cough;
Female;
Fungi;
Hemorrhage;
Humans;
Incidence;
Kidney;
Kidney Transplantation;
Liver;
Living Donors;
Lung;
Middle Aged;
Opportunistic Infections;
Pyrimidines;
Sensation;
Transplants;
Triazoles
- From:The Journal of the Korean Society for Transplantation
2012;26(3):202-206
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Invasive opportunistic infection by Aspergillus fungus is life-threatening for kidney transplant recipients. The occurrence of aspergillosis by hematogenous dissemination can affect multiple organs. Despite having a lower incidence rate relative to bacterial or viral infections in kidney transplant recipients, fungal infections produce the highest number of mortalities. We report a simultaneous case of invasive aspergillosis in the lung and liver of a 52-year-old female patient who underwent living donor kidney transplant. She suffered massive blood loss and high-volume transfusions due to postoperative bleeding. One month after transplantation, she reported intermittent coughing without febrile sensation. Computed tomography revealed nodules on the right and left upper lobes of the lung and multiple cystic liver lesions. Based on pathologic findings and culture from aspirate, she was diagnosed with invasive aspergillosis involving the liver and lung. After a 4 month voriconazole treatment the nodules in the lung and liver disappeared.