Alberta Stroke Program Early CT Score in the Prognostication after Endovascular Treatment for Ischemic Stroke: A Meta-analysis.
10.5469/neuroint.2017.12.1.20
- Author:
Chang Woo RYU
1
;
Hee Shup SHIN
;
Soonchan PARK
;
Sang Hyun SUH
;
Jun Seok KOH
;
Hye Yeon CHOI
Author Information
1. Department of Radiology, Kyung Hee University Hospital at Gangdong, School of Medicine, Kyung Hee University, Seoul, South Korea. md.cwryu@gmail.com
- Publication Type:Meta-Analysis ; Original Article
- Keywords:
ASPECTS score;
Stroke;
Thrombectomy;
Reperfusion therapy
- MeSH:
Alberta*;
Brain;
Humans;
Middle Cerebral Artery;
Stroke*;
Thrombectomy
- From:Neurointervention
2017;12(1):20-30
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The Alberta Stroke Program Early CT Score (ASPECTS) was devised to quantify the extent of early ischemic changes in the middle cerebral artery territory on brain CT. We performed a systematic review and meta-analysis of studies that presented clinical outcomes and baseline ASPECTS in ischemic stroke patients managed with endovascular methods to validate the use of ASPECTS for risk prognostication. MATERIALS AND METHODS: We searched the MEDLINE, EMBASE, and Cochran databases for observational or interventional studies that reported clinical outcomes and baseline ASPECTS in ischemic stroke patients treated with endovascular methods. Data were pooled to perform a meta-analysis for comparisons of clinical outcomes between high and low ASPECTS patients. RESULTS: A meta-analysis of 13 studies (six observational and seven interventional) revealed favorable outcomes (mRS sore 0-2 at 90 days) for high baseline ASPECTS (odds ratio=2.22; 95% CI: 1.74-2.86). CONCLUSION: High ASPECTS is a predictor of favorable outcome after endovascular therapy for ischemic stroke.
