In Vitro Evaluation of Fusiform-Shaped Stents for Wide-Neck Intracranial Aneurysm Treatment.
10.5469/neuroint.2018.00976
- Author:
Zhen Yu JIA
1
;
Yuan Yuan JIANG
;
Jung Min WOO
;
Seon Moon HWANG
;
Ok Kyun LIM
;
Tae Il KIM
;
Jung Cheol PARK
;
Hee Sun LEE
;
Eun Sang KIM
;
Deok Hee LEE
Author Information
1. Departments of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. dhlee@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Intracranial aneurysm;
Endovascular procedure;
Stents;
Self-expandable metal stent;
Proof of concept experiment
- MeSH:
Aneurysm;
Arteries;
Cell Size;
Endovascular Procedures;
Humans;
In Vitro Techniques*;
Intracranial Aneurysm*;
Neck;
Parents;
Stents*
- From:Neurointervention
2018;13(2):117-123
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Wide-neck aneurysms (WNAs) associated with a dilated parent artery (PA) are not uncommon morphological abnormalities and usually cause inappropriate wall apposition and incomplete neck coverage of a tubular stent in stent-assisted coiling of aneurysms. We aimed to introduce a fusiform-shaped stent (FSS) and test its effectiveness in treating intracranial WNAs associated with a dilated PA using a three-dimensional (3D) model. MATERIALS AND METHODS: Two FSS types were designed with the middle one-third segment dilated by 10% (FSS10) and 20% (FSS20) and were compared with the tubular-shaped stent (TSS). A patient-specific 3D WNA model was prototyped and produced, and in vitro stent placement was performed. Angiographic images of the three stent types were analyzed and compared using predetermined parameters. RESULTS: The stent lumens were significantly larger in FSS10 and FSS20 than in TSS in the middle segments (P=0.046), particularly FSS20 (P=0.018). The non-covered area at the ostium tended to be smaller in FSS10 and FSS20 than in TSS, but the difference was not significant (P>0.05). The stent length was significantly longer in FSS10 and FSS20 than in TSS. The stent cell size was significantly larger in FSS than in TSS. CONCLUSION: Better vessel wall apposition and aneurysmal neck coverage was observed for FSS than for TSS. No significant difference was observed between FSS10 and FSS20.
