In Vitro Antifungal Activity of Equol against Candida albicans.
- Author:
Jeong Ah LEE
1
;
Hee Youn CHEE
Author Information
1. Department of Cell Biology, College of Medicine, Konyang University, Daejeon 302-718, Korea. hychee@konyang.ac.kr
- Publication Type:In Vitro ; Brief Communication
- Keywords:
Candida albicans;
Equol;
Fungicidal activities
- MeSH:
Candida;
Candida albicans;
Cell Membrane;
Equol;
Membranes;
Microscopy, Electron, Scanning
- From:Mycobiology
2010;38(4):328-330
- CountryRepublic of Korea
- Language:English
-
Abstract:
In this study, we demonstrate that equol has fungicidal activities against Candida albicans. The minimum inhibitory and minimum fungicidal concentrations of equol against C. albicans were 516 and 1,032 microM, respectively. Two separate viability assays found that equol changed the integrity of the C. albicans cell membrane, possibly by formation of membrane lesions. Scanning electron microscopy demonstrated ultrastructural changes.
