Antimicrobial Activity of Some Schiff Bases Derived from Benzoin, Salicylaldehyde, Aminophenol and 2,4 Dinitrophenyl Hydrazine.
10.4489/MYCO.2008.36.1.070
- Author:
Mele JESMIN
1
;
M Mohsin ALI
;
M S SALAHUDDIN
;
M Rowshanul HABIB
;
Jahan Ara KHANAM
Author Information
1. Department of Applied Chemistry and Chemical Technology, Rajshahi University, Rajshahi-6205, Bangladesh. akazadplabon@yahoo.com
- Publication Type:Original Article
- Keywords:
Antimicrobial activity;
Cytotoxicity;
Schiff base
- MeSH:
Aldehydes;
Anti-Infective Agents;
Bacteria;
Benzoin;
Fungi;
Hydrazines;
Nystatin;
Schiff Bases
- From:Mycobiology
2008;36(1):70-73
- CountryRepublic of Korea
- Language:English
-
Abstract:
The antibacterial and antifungal activities of three schiff bases were evaluated against some pathogenic bacteria and fungi. Parallel experiments were also carried out with standard drugs (Kanamycin for bacteria and Nystatin for fungi). Two compounds [N-(1-phenyl-2-hydroxy-2phenylethylidine)-2',4' dinitrophenyl hydrazine, abbreviated as PDH and N-(2-hydroxy benzylidine)-2'-hydroxy imine, abbreviated as HHP] showed significant antimicrobial activities. The rest one [N-(1-phenyl 2-hydroxy-2 phenyl ethylidine) 2'-hydroxy phenyl imine, abbreviated as PHP] showed moderate activity. All these three compounds were found to possess pronounced cytotoxic effect. These compounds can be considered as potent antimicrobial agents.
