The Histologic Features of the Uterus and Adnexa Extirpated from Gender Identity Disorder Patients with Depot Androgen Injection.
- Author:
Jae Chun BYUN
;
Bong Gyu KWAK
;
Ji Hyun SHIN
;
Moon Seok CHA
;
Myoung Seok HAN
;
Seo Hee RHA
;
Seok Kwun KIM
- Publication Type:Original Article
- Keywords:
Gender identity disorder (GID);
Androgen therapy;
Atrophy
- MeSH:
Atrophy;
Cervix Uteri;
Corpus Luteum;
Endometrium;
Epithelium;
Female;
Gender Identity*;
Humans;
Ovary;
Uterus*
- From:Korean Journal of Fertility and Sterility
2005;32(4):325-330
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To investigate the histologic features of the uterus and adnexae extirpated from gender identity disorder (GID) patients that received depot androgen injection. METHODS: We reviewed the histologic findings of the uterus and adnexae removed from sixteen GID patients, who had taken depot androgen injection for 5~168 months. RESULTS: Fourteen patients (87.5%) showed the atrophied epithelium of exocervix and all of 16 patients (100%) showed the atrophy of endometrium. Seven patients (43.7%) showed multiple cystic follicles in the ovarian cortex and 6 patients (37.5%), 3 patients (18.7%) showed corpus albicans and corpus luteum, respectively. CONCLUSIONS: Exogenous androgen induced atrophy of cervix and endometrium. This effect was more prominent in the endometrium. In addition, PCO-like histologic features were observed in the ovary.
