Antitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus.
- Author:
June Woo LEE
1
;
Seong Jin BAEK
;
Woo Chul BAE
;
Jeong Min PARK
;
Yong Seok KIM
Author Information
1. Department of Food Processing and Cooking, Kyungbuk College, Yeongjusi 750-712, Korea.
- Publication Type:Original Article
- Keywords:
Antioxidant;
Antitumor;
Immunostimulation;
Phellinus linteus;
Polysaccharide
- MeSH:
Absorption;
Alanine;
Alkalies;
Aspartic Acid;
Chromatography, Gel;
Fruit*;
Immunization;
Molecular Weight;
Water
- From:Mycobiology
2006;34(4):230-235
- CountryRepublic of Korea
- Language:English
-
Abstract:
Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively. Amino acid pattern showed that two extracts contained large amount of aspartic acid and alanine. Two extracts showed characteristic IR absorption pattern for glycosidic bond at 890 cm(-1). PL-H was divided two fractions by gel filtration chromatography and the molecular weights of each fraction were estimated to be about 10 kD and 225 kD, respectively and also PL-A was estimated 10 kD. Two extracts showed strong antitumor, immunomodulating and antioxidant activities, and were compared with commercialized glycopeptide anticancer drugs.
