Isolation, Identification and Characterization of a Antidementia Acetylcholinesterase Inhibitor-Producing Yarrowia lipolytica S-3.
- Author:
Min Gu KANG
1
;
Min Ho YOON
;
Young Jun CHOI
;
Jong Soo LEE
Author Information
1. Department of Life Science and Genetic Engineering, PaiChai University, Daejeon 302-735, Korea. biotech8@pcu.ac.kr
- Publication Type:Original Article
- Keywords:
Antidementia acetylcholinesterase inhibitor;
Yarrowia lipolytica S-3;
26S rDNA sequences
- MeSH:
Acetylcholinesterase;
DNA, Ribosomal;
Ethanol;
Glucose;
Sprains and Strains;
Yarrowia;
Yeasts
- From:Mycobiology
2012;40(1):42-46
- CountryRepublic of Korea
- Language:English
-
Abstract:
This report describes the isolation and identification of a potent acetylcholinesterase (AChE) inhibitor-producing yeasts. Of 731 species of yeast strain, the S-3 strain was selected as a potent producer of AChE inhibitor. The selected S-3 strain was investigated for its microbiological characteristics. The S-3 strain was found to be short-oval yeast that did not form an ascospore. The strain formed a pseudomycelium and grew in yeast malt medium containing 50% glucose and 10% ethanol. Finally, the S-3 strain was identified by its physiological characteristics and 26S ribosomal DNA sequences as Yarrowia lipolytica S-3.
