In vitro Evaluation of Antidermatophytic Activity of Egyptian Bee Propolis in Combination with Plant Essential Oils in Sheep Hoof Plate: An Experimental Model.
- Author:
Yehia A G MAHMOUD
1
Author Information
1. Tanta University, Faculty of Science, Botany Department, Mycology research lab. Tanta 31527, Egypt. yehiam@decl.tanta.edu.eg
- Publication Type:In Vitro ; Original Article
- Keywords:
Antifungal drugs;
Bee propolis;
Dermatophytes;
Plant essential oils
- MeSH:
Animals;
Arthrodermataceae;
Bees*;
Clotrimazole;
Ethanol;
Syzygium;
Hoof and Claw*;
Humans;
Jasminum;
Mentha;
Models, Theoretical*;
Ocimum basilicum;
Oils, Volatile*;
Olea;
Plants*;
Propolis*;
Rosa;
Sheep*
- From:Mycobiology
2003;31(2):99-104
- CountryRepublic of Korea
- Language:English
-
Abstract:
Bee propolis ethanolic extract with some plant essential oils was investigated for its antidermatophytic properties. The tested plant essential oils included jasmine, clove, lemon, Arabian jasmine, mint, rosa, olive and basil. The antidermatophytic activity has been compared to Naftifine-HCl and Clotrimazole used for dermatophyte treatment. Experimental model has been tested using sheep hoof plate for the in vitro tests to stimulate human nails. Mint, clove and basil with 4 mg/ml of bee propolis have a comparable efficacy to those of Naftifine-HCl and Clotrimazole. There is a great necessity for new effective low price and safe antidermatophyte agents to avoid recurrent infection. Propolis synergistic could be of great importance with essential oils of plants in dermatophyte therapy.
