In Vitro Observation of Air Bubbles during Delivery of Various Detachable Aneurysm Embolization Coils.
10.3348/kjr.2012.13.4.412
- Author:
Deok Hee LEE
1
;
Seon Moon HWANG
;
Ok Kyun LIM
;
Jae Kyun KIM
Author Information
1. Department of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Korea. dhlee@amc.seoul.kr
- Publication Type:Original Article ; Comparative Study ; In Vitro ; Research Support, Non-U.S. Gov't
- Keywords:
Air bubble;
Air embolization;
Cerebral aneurysm;
Embolization coil;
Detachable coil
- MeSH:
Embolism, Air/*etiology;
Embolization, Therapeutic/*adverse effects/*instrumentation;
Intracranial Embolism/*etiology;
Magnetic Resonance Imaging/methods;
Microscopy;
Risk Assessment;
Statistics, Nonparametric
- From:Korean Journal of Radiology
2012;13(4):412-416
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: Device- or technique-related air embolism is a drawback of various neuro-endovascular procedures. Detachable aneurysm embolization coils can be sources of such air bubbles. We therefore assessed the formation of air bubbles during in vitro delivery of various detachable coils. MATERIALS AND METHODS: A closed circuit simulating a typical endovascular coiling procedure was primed with saline solution degassed by a sonification device. Thirty commercially available detachable coils (7 Axium, 4 GDCs, 5 MicroPlex, 7 Target, and 7 Trufill coils) were tested by using the standard coil flushing and delivery techniques suggested by each manufacturer. The emergence of any air bubbles was monitored with a digital microscope and the images were captured to measure total volumes of air bubbles during coil insertion and detachment and after coil pusher removal. RESULTS: Air bubbles were seen during insertion or removal of 23 of 30 coils (76.7%), with volumes ranging from 0 to 23.42 mm3 (median: 0.16 mm3). Air bubbles were observed most frequently after removal of the coil pusher. Significantly larger amounts of air bubbles were observed in Target coils. CONCLUSION: Variable volumes of air bubbles are observed while delivering detachable embolization coils, particularly after removal of the coil pusher and especially with Target coils.
