Overlap Between Asthma and COPD: Where the Two Diseases Converge.
10.4168/aair.2010.2.4.209
- Author:
So Ri KIM
1
;
Yang Keun RHEE
Author Information
1. Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, Korea. ryk@chonbuk.ac.kr
- Publication Type:Review
- Keywords:
Asthma;
COPD;
overlap;
exacerbation;
remodeling
- MeSH:
Adult;
Airway Obstruction;
Asthma;
Bronchodilator Agents;
Eosinophilia;
Eosinophils;
Humans;
Hypersensitivity;
Inflammation;
Neutrophils;
Pulmonary Disease, Chronic Obstructive;
Risk Factors;
Smoke
- From:Allergy, Asthma & Immunology Research
2010;2(4):209-214
- CountryRepublic of Korea
- Language:English
-
Abstract:
Asthma and chronic obstructive pulmonary disease (COPD) are traditionally recognized as distinct diseases, with some clearly separate characteristic. Asthma originates in childhood, is associated with allergies and eosinophils, and is best treated by targeting inflammation, whereas COPD occurs in adults who smoke, involves neutrophils, and is best treated with bronchodilators and the removal of risk factors. However, the distinction between the two is not always clear. Patients with severe asthma may present with fixed airway obstruction, and patients with COPD may have hyperresponsiveness and eosinophilia. Recognizing and understanding these overlapping features may offer new insight into the mechanisms and treatment of chronic airway inflammatory diseases.
