Analysis of Risk Factors for Developmental Delay in Preterm Infants Using Screening Test.
10.26815/jkcns.2018.26.3.146
- Author:
Seong Eun CHOI
1
;
Kon Hee LEE
Author Information
1. Department of Pediatrics, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea. headaches77@gmail.com
- Publication Type:Original Article
- Keywords:
Preterm infant;
Developmental delays;
Risk factors;
Developmental screening test
- MeSH:
Apgar Score;
Birth Weight;
Dexamethasone;
Early Diagnosis;
Follow-Up Studies;
Gestational Age;
Heart;
Hemorrhage;
Humans;
Infant;
Infant, Newborn;
Infant, Premature*;
Intensive Care, Neonatal;
Logistic Models;
Lung Diseases;
Mass Screening*;
Problem Solving;
Retinopathy of Prematurity;
Risk Factors*;
Sepsis;
Ventilators, Mechanical
- From:
Journal of the Korean Child Neurology Society
2018;26(3):146-151
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The purpose of this study was to identify the risk factors for developmental delays in preterm infants. METHODS: We studied 151 preterm infants admitted to the neonatal intensive care unit (NICU) at the Hallym University Kangnam Sacred Heart Hospital from January 2013 to November 2016. After discharge, the infants were evaluated by a pediatric neurologist via the developmental screening test K-ASQ:SE II, which consists of five domains: communication (CC), gross motor (GM), fine motor (FM), problem solving (PS), and social-emotional (SE). The subjects were divided into a normal group and an abnormal group (abnormal results on at least one of the five domains). Several variables were compared between the two groups and risk factors for developmental delays were analyzed. RESULTS: Several factors, such as birth weight (BW), gestational age (GA), Apgar score at 1 and 5 min (AS1, AS5), hospital days (HDs), respiratory distress syndrome (RDS), chronic lung diseases, intraventricular hemorrhage (IVH), early sepsis, retinopathy of prematurity (ROP), and history of management of invasive ventilators, dexamethasone, anti-hypotensive, were significantly different between the normal and abnormal groups. BW was a risk factor for developmental delay according to the binary logistic regression analysis. On individual domain analysis, risk factors were lower GA for domains CC and FM, lower AS1 for GM domain, lower BW for PS domain, and longer HDs for SE domain. CONCLUSION: In preterm infants, regular developmental screening especially follow-up observation, is important for early detection of developmental delay, considering the risk factors, such as GA (≤30 weeks), BW (≤1,500 g), low AS1, and long HDs, which may be helpful in the early diagnosis of developmental delay.
