Seasonal acclimation in sudomotor function evaluated by QSART in healthy humans.
10.4196/kjpp.2016.20.5.499
- Author:
Young Oh SHIN
1
;
Jeong Beom LEE
;
Jeong Ho KIM
Author Information
1. Department of Physiology, College of Medicine, Soonchunhyang University, Cheonan 31151, Korea. leejb@sch.ac.kr
- Publication Type:Original Article
- Keywords:
Acetylcholine (ACh);
QSART (quantitative sudomotor axon reflex testing);
Seasonal acclimation;
Sweat
- MeSH:
Acclimatization*;
Acetylcholine;
Axons;
Basal Metabolism;
Body Temperature;
Humans*;
Iontophoresis;
Peripheral Nervous System;
Reflex;
Republic of Korea;
Seasons*;
Skin Temperature;
Sweat;
Sweat Glands;
Sweating
- From:The Korean Journal of Physiology and Pharmacology
2016;20(5):499-505
- CountryRepublic of Korea
- Language:English
-
Abstract:
The quantitative sudomotor axon reflex testing (QSART) is a classic test of routine postganglionic sudomotor function. We investigated sudomotor function by QSART after summer (July 2012) and winter (January 2013) seasonal acclimation (SA) in the Republic of Korea. QSART with acetylcholine (ACh) iontophoresis were performed to determine directly activated (DIR) and axon reflex-mediated (AXR1, 2) sweating rate. Onset time of axon reflex, activated sweat gland density (ASGD), activated sweat gland output (ASGO), tympanic and skin temperatures (T(ty), T(sk)), basal metabolic rate (BMR), and evaporative loss volume changes were measured. Tympanic and mean body temperature (T(b); calculated from T(ty), T(sk)) were significantly lower after summer-SA than that of winter-SA. Sweat onset time was delayed during winter-SA compared to that after summer-SA. BMR, AXR(1), AXR(2), and DIR sweat rates, ASGD and ASGO, and evaporative loss volume were significantly diminished after winter-SA relative to after summer-SA. In conclusion, changes in sweating activity measured by QSART confirmed the involvement of the peripheral nervous system in variation of sudomotor activity in seasonal acclimation.
