Prognostic factor analysis in curatively resected early gastric cancer.
- Author:
Young Rok DO
1
;
Yong Jin KIM
;
Jin Young KIM
;
Ju Yeon CHO
;
Ji An HUR
;
Hong Suk SONG
;
In Ho KIM
;
Su Sang SOHN
Author Information
1. Department of Internal Medicine, Keimyung University School of Medicine, Dongsan Medical Center, Daegu, Korea. shs7436@dsmc.or.kr
- Publication Type:Original Article
- Keywords:
Gastric cancer;
Prognosis
- MeSH:
Cause of Death;
Factor Analysis, Statistical*;
Humans;
Incidence;
Korea;
Lymph Nodes;
Prognosis;
Recurrence;
Retrospective Studies;
Stomach Neoplasms*;
Survival Rate
- From:Korean Journal of Medicine
2004;66(2):120-126
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Gastric cancer is the most frequent cancer and second leading cause of death from cancer in Korea. The prognosis of early gastric cancer (EGC) is generally excellent and the proportion of EGC cases is steadily increasing nowadays. We need to find out the best treatment modality of EGC. So, the authors analyse the prognostic factors in curatively resected early gastric cancer. METHODS: Retrospective analysis was performed for 598 EGC cases which underwent curative resection in Dongsan Medical Center from 1996 to 2001. In this study, several factors such as age, sex, depth of invasion, lymph node involvement, tumor size, histologic grade and operation method were evaluated to determine the prognostic significance. RESULTS: The incidence of EGC among all gastric cancer was 28.4%. Five year total survival rate and relapse free survival rate of early gastric cancer were 94.3% and 95.8% respectively. Median survival time was 82.7 months. In Cox regression analysis, age and lymph node status shows statistical significance in predicting prognosis. CONCLUSION: In curatively resected EGC patients, 5-year total survival rate and relapse free survival rate were 94.3% and 95.8%. Age and lymph node involvement were independent prognostic factor for the total survival rate.