MicroRNA-1 in Cardiac Diseases and Cancers.
10.4196/kjpp.2014.18.5.359
- Author:
Jianzhe LI
1
;
Xiaomin DONG
;
Zhongping WANG
;
Jianhua WU
Author Information
1. Department of Pharmacy, Ruikang Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi 530011, China.
- Publication Type:Review
- Keywords:
Cancers;
Cardiac diseases;
MicroRNA-1
- MeSH:
Gene Expression Regulation;
Heart Diseases*;
MicroRNAs;
Pathologic Processes;
RNA, Untranslated
- From:The Korean Journal of Physiology and Pharmacology
2014;18(5):359-363
- CountryRepublic of Korea
- Language:English
-
Abstract:
MicroRNAs (miRs) are endogenous approximately22-nt non-coding RNAs that participate in the regulation of gene expression at post-transcriptional level. MiR-1 is one of the muscle-specific miRs, aberrant expression of miR-1 plays important roles in many physiological and pathological processes. In this review, we focus on the recent studies about miR-1 in cardiac diseases and cancers. The findings indicate that miR-1 may be a novel, important biomarker, and a potential therapeutic target in cardiac diseases and cancers.
