A case of IgA nephropathy with systemic lupus erythematosus.
- Author:
Hyun Wook KIM
1
;
Shin Wook KANG
;
Kyu Hun CHOI
;
Ho Yung LEE
;
Dae Suk HAN
;
Jeong Hae KIE
;
Hyeon Joo JEONG
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. khchoi6@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Glomerulonephritis;
IgA;
Lupus Erythematosus;
Sytemic
- MeSH:
Aged;
Anemia, Hemolytic;
Arthralgia;
Arthritis;
Biopsy;
Classification;
Diagnosis;
Edema;
Female;
Glomerulonephritis;
Glomerulonephritis, IGA*;
Hematuria;
Humans;
Immunoglobulin A*;
Kidney Failure, Chronic;
Lupus Coagulation Inhibitor;
Lupus Erythematosus, Systemic*;
Lupus Nephritis;
Oral Ulcer;
Prevalence;
Proteinuria
- From:Korean Journal of Medicine
2004;66(2):190-194
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In systemic lupus erythematosus patients, prevalence of renal involvement is high, even in the absence of overt clinical manifestation. Lupus nephritis can usually be categorized according to the widely used WHO classification. however, clinically significant renal disease unrelated to lupus nephritis have rarely been described in patients with SLE. Especially, there has been few reported cases of IgA nephropathy with SLE since first reported in 1995, but their relationship is not apparent yet. We experienced a 72-year-old female who was admitted to our hospital due to generalized edema, arthralgia, proteinuria, microscopic hematuria. Her diagnosis of IgA nephropathy was estabilished on biopsy. At the same time, she was diagnosed as SLE. in that the serology for ANA was positive at 1:640, lupus anticoagulant and anti-cardiolipin antibody were positive, hemolytic anemia, arthritis and oral ulcer. and eventually she was diagnosed end-stage renal disease 2 months later. In conclusion, atypical glomerular lesion in SLE should raise the possibility of a non-lupus glomerulopathy, including IgA nephropathy.
