A case of bullous pyoderma gangrenosum associated with refractory acute biphenotypic leukemia.
- Author:
Hee Jung KANG
1
;
Jae Lyun LEE
;
Kyung Hee LEE
;
Myung Soo HYUN
;
Dong Hoon SHIN
;
Jin Woo PARK
;
Hee Soon CHO
Author Information
1. Division of Hematology-Oncology, Department of Medicine, Yeungnam University College of Medicine, Daegu, Korea. hms@med.yu.ac.kr
- Publication Type:Case Report
- Keywords:
Pyoderma gangrenosum;
Acute leukemia
- MeSH:
Leukemia;
Leukemia, Biphenotypic, Acute*;
Leukemia, Lymphoid;
Lymphocytes;
Neutrophils;
Phenotype;
Pyoderma Gangrenosum*;
Pyoderma*;
Skin;
Skin Diseases
- From:Korean Journal of Medicine
2004;66(2):200-203
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pyoderma gangrenosum is a neutrophilic dermatosis that may be associated acute leukemia. We report a case of pyoderma gangrenosum associated refractory acute biphenotypic leukemia wherein the malignant cells show a phenotype specific for myelogenous and lymphocytic leukemia. Histopathologic examination revealed moderate perivascular infiltrate consisting mainly of neutrophils and lymphocytes without involvement of leukemic cells in the skin lesions. Treatment with systemic steroid was followed by a characteristically rapid healing of the skin lesions.
