Atypical beta-Catenin Activated Child Hepatocellular Tumor.
10.5223/pghn.2015.18.2.144
- Author:
Aynur TURAN
1
;
Havva Akmaz UNLU
;
Esra KARAKUS
;
Arzu YAZAL ERDEM
;
Zeynep Ilerisoy YAKUT
Author Information
1. Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey. aturanrad@gmail.com
- Publication Type:Case Report
- Keywords:
Adenoma;
Liver;
Hepatocellular carcinoma;
Magnetic resonance imaging;
Beta-catenin
- MeSH:
Adenoma;
Adenoma, Liver Cell;
beta Catenin*;
Carcinoma, Hepatocellular;
Child*;
Hepatocytes;
Humans;
Liver;
Liver Neoplasms;
Magnetic Resonance Imaging
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2015;18(2):144-148
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hepatocellular adenomas are a benign, focal, hepatic neoplasm that have been divided into four subtypes according to the genetic and pathological features. The beta-catenin activated subtype accounts for 10-15% of all hepatocellular adenomas and specific magnetic resonance imaging features have been defined for different hepatocellular adenomas subtypes. The current study aimed to report the magnetic resonance imaging features of a well differentiated hepatocellular carcinoma that developed on the basis of beta-catenin activated hepatocellular adenomas in a child. In this case, atypical diffuse steatosis was determined in the lesion. In the literature, diffuse steatosis, which is defined as a feature of the hepatocyte nuclear factor-1alpha-inactivated hepatocellular adenomas subtype, has not been previously reported in any beta-catenin activated hepatocellular adenomas case. Interlacing magnetic resonance imaging findings between subtypes show that there are still many mysteries about this topic and larger studies are warranted.
