Indocyanine Green Angiographic Features of Myopic Subfoveal Choroidal Neovascularization as a Prognostic Factor after Photodynamic Therapy.
- Author:
Suk Ho BYEON
1
;
Oh Woong KWON
;
Sung Chul LEE
;
Sung Soo KIM
;
Hyoung Jun KOH
Author Information
- Publication Type:Original Article ; Comparative Study
- Keywords: Choroidal neovascularization (CNV); Degenerative myopia; Dark rim; Indocyanine green angiography (ICG); Myopia
- MeSH: Visual Acuity; Retrospective Studies; Prognosis; *Photochemotherapy; Myopia/*complications/pathology; Middle Aged; Male; Indocyanine Green/*diagnostic use; Humans; Fundus Oculi; Fovea Centralis/*pathology; Follow-Up Studies; Fluorescein Angiography/*methods; Female; Coloring Agents/*diagnostic use; Choroidal Neovascularization/complications/drug therapy/*pathology; Aged; Adult
- From:Korean Journal of Ophthalmology 2006;20(1):18-25
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: To determine the influence of clinical features and Indocyanine green (ICG) angiographic features on the visual outcome of patients with myopic sub-foveal choroidal neovascularization (CNV) who received photodynamic therapy (PDT). METHODS: Thirty-six consecutive patients (39 eyes) with myopic CNV who were followed up for more than one year after PDT were enrolled in this study. Clinical features included age, gender, refractive error, great linear dimension, and subretinal hemorrhage. ICG features included the lesion size, lacquer cracks, hypofluorescence surrounding the CNV (dark rim), peripapillary atrophy size, and visible prominent choroidal veins under the macula. Linear regression analysis was performed using the change in visual acuity (delta logMAR) as the dependent variable and the above factors as independent variables. RESULTS: At one-year follow-up after PDT, a younger age (p=0.002) and the presence of a dark rim (p=0.002) were significantly correlated with an improvement of visual acuity (decrement in logMAR) after PDT. Other factors had no significant influence on changes in visual acuity. CONCLUSIONS: Younger patients and patients with a dark rim on ICG angiography had a higher chance of visual improvement after PDT in myopic CNV.
