A Case of Alveolar Rhabdomyosarcoma of the Ethmoid Sinus Invading the Orbit in an Adult.
- Author:
Hyun Seung MOON
1
;
Sang Won KWON
;
Jong Hyeok LEE
Author Information
- Publication Type:Case Report
- Keywords: Adult rhabdomyosarcoma; Ethmoid; Orbital tumor
- MeSH: Tomography, X-Ray Computed; Rhabdomyosarcoma, Alveolar/*pathology/radiography; Paranasal Sinus Neoplasms/*pathology/radiography; Orbital Neoplasms/*pathology/radiography; Neoplasm Invasiveness; Middle Aged; Male; Magnetic Resonance Imaging; Humans; *Ethmoid Sinus; Diagnosis, Differential; Biopsy
- From:Korean Journal of Ophthalmology 2006;20(1):70-75
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: A case study and literature review of alveolar rhabdomyosarcoma (RMS) in an adult. METHODS: A 48-year-old male patient presented at our clinic complaining of proptosis that had persisted for 2 weeks in his left eye. A computed tomography (CT) scan revealed a destructive soft-tissue mass in the left ethmoid sinus with invasion of the left orbit and compression of the medial rectus muscle. Endoscopic intranasal biopsy revealed alveolar RMS. Conservative debulking and orbital wall decompression were performed. RESULTS: Immunohistochemical testing was positive for desmin, S-100, and smooth muscle actin (SMA), supporting the diagnosis of RMS. Since ipsilateral cervical and spinal metastasis was detected, systemic treatment was administered simultaneously. CONCLUSIONS: Although rarely found in adults, RMS should be considered in the differential diagnosis of orbital tumors. Immunohistochemical analysis plays an important role in the definitive diagnosis of RMS.
