- Author:
Geum Youn GWAK
1
Author Information
- Publication Type:Original Article
- Keywords: Non-alcoholic fatty liver disease; Nonalcoholic steatohepatitis; Diagnosis; Liver biopsy
- MeSH: Biomarkers; Biopsy; Diagnosis*; Diagnostic Tests, Routine; Elasticity Imaging Techniques; Fatty Liver*; Fibrosis; Humans; Liver; Prognosis
- From:Journal of Korean Diabetes 2014;15(2):82-92
- CountryRepublic of Korea
- Language:Korean
- Abstract: Although the classical gold standard for diagnosing and staging non-alcoholic fatty liver disease (NAFLD) and assessing fibrosis is liver biopsy, the procedure has several drawbacks, such as sample error, subjectivity in interpretation, high cost, and a small but real risk of complications.In an attempt to replace liver biopsy and to subcategorize patients with NAFLD into different prognoses, many non-invasive methods using various biomarkers, scoring systems, and imaging methods, such as elastography, have been attempted in the last decade. This article summarizes non-invasive diagnostic tests for the diagnosis of NAFLD/Nonalcoholic steatohepatitis, as well as the limitations and merits of liver biopsy.