Mechanism and Efficacy of New Anti-diabetic Medications.
10.4093/jkd.2012.13.4.167
- Author:
Hyuk Sang KWON
1
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea. drkwon@catholic.ac.kr
- Publication Type:Editorial
- Keywords:
Type 2 diabetes mellitus;
Medication
- MeSH:
Diabetes Mellitus, Type 2;
Glucose;
Incretins;
Insulin;
Insulin Resistance;
Neurotransmitter Agents
- From:Journal of Korean Diabetes
2012;13(4):167-171
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Previously proposed main pathogenic mechanisms for type 2 diabetes mellitus (T2DM) are increased hepatic glucose production, insulin resistance and insulin secretion defect. However, further mechanisms involved in the development of T2DM such as decreased incretin effect, increased glucose reabsorption and neurotransmitter dysfunction have been proposed recently. Based on these findings, various medications for glycemic control in T2DM are developing. In this review article, I will focus on the mechanisms and efficacies of up-coming new diabetes medications.
