Diabetes and Vitamin D.
10.4093/jkd.2013.14.4.190
- Author:
Jin Hee PARK
1
;
Mee Kyoung KIM
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. makung@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Vitamin D;
Diabetes mellitus;
Obesity
- MeSH:
Calcium;
Diabetes Mellitus;
Diabetes Mellitus, Type 2;
Insulin Resistance;
Metabolism;
Obesity;
Risk Factors;
Vitamin D Deficiency;
Vitamin D*;
Vitamins*
- From:Journal of Korean Diabetes
2013;14(4):190-193
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Recent cross-sectional and prospective studies suggest an association between vitamin D deficiency and type 2 diabetes mellitus risk. Vitamin D metabolism may play a role in diabetes mellitus pathogenesis independently of known risk factors. The decrease in vitamin D levels may occur through several mechanisms such as a decrease in the calcium concentration, an increase in parathyroid hormones, or a direct effect of vitamin D on worsening insulin resistance and secretion, thus augmenting the risk of developing type 2 diabetes. However, doubt remains as to whether low vitamin D levels are causal or merely a marker of worse disease or worse health status. Interventional studies have provided conflicting and inconclusive results due to the different populations studies, dose and time frame of vitamin D supplementation. Further studies are required.
