Medical Therapy in Pregnant Women with Diabetes.
10.4093/jkd.2011.12.4.201
- Author:
Seok Hong LEE
1
;
Jihyun AHN
;
Jaetaek KIM
Author Information
1. Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea. jtkim@cau.ac.kr
- Publication Type:Original Article
- Keywords:
Pregnancy;
Gestational diabetes;
Insulin;
Hypoglycemic agents;
Oral administration
- MeSH:
Abortion, Spontaneous;
Administration, Oral;
Complementary Therapies;
Diabetes, Gestational;
Female;
Glucose;
Glyburide;
Humans;
Hypoglycemic Agents;
Insulin;
Insulin, Long-Acting;
Insulin, Short-Acting;
Life Style;
Metformin;
Perinatal Mortality;
Pregnancy;
Pregnant Women;
Premature Birth;
Resin Cements
- From:Journal of Korean Diabetes
2011;12(4):201-204
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pregnant women with diabetes are at greater risk for adverse outcomes, such as miscarriage, macrosomia, and preterm birth. Advances in the care of diabetes have reduced maternal and perinatal mortality rates to the levels expected in nondiabetic pregnancies. Lifestyle modification such as medical nutritional therapy and exercise is a first step in therapy for gestational diabetes. Rapid-acting insulin analogs (lispro, aspart) are comparable in safety and superior in glucose control to regular human insulin. Because the safety of long-acting insulin analogs (glargine, detemir) in pregnancy has not firmly established, the use of human insulin is preferred over basal insulin. Among the oral hypoglycemic agents, metformin and glyburide might be considered as alternative therapies.
