- Author:
Joon Young SONG
1
Author Information
- Publication Type:Original Article
- Keywords: Diabetes; Foot infection; Antimicrobial agent; Empirical therapy
- MeSH: Diabetic Foot; Gram-Positive Cocci; Humans; Staphylococcus aureus; Ulcer
- From:Journal of Korean Diabetes 2011;12(2):83-87
- CountryRepublic of Korea
- Language:Korean
- Abstract: Treatment of diabetic foot infection remains a challenging issue to be solved. Bacterial species complicating diabetic foot ulcer differ from those of non-diabetic patients. Empirical antibiotic regimens are selected based on the severity and type of infection (acute infection versus chronic infection), which should always include coverage for aerobic Gram-positive cocci, especially Staphylococcus aureus. Narrow-spectrum antibiotic agents are considered for mild-to-moderate, recent infections, while broad-spectrum agents are usually required for severe, chronic infections, targeting both Gram-positive cocci and Gram-negative bacilli.